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Epstein-Barr virus evades restrictive host chromatin closure by subverting B cell activation and germinal center regulatory loci

Chromatin accessibility fundamentally governs gene expression and biological response programs that can be manipulated by pathogens. Here we capture dynamic chromatin landscapes of individual B cells during Epstein-Barr virus (EBV) infection. EBV(+) cells that exhibit arrest via antiviral sensing an...

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Detalles Bibliográficos
Autores principales: SoRelle, Elliott D., Reinoso-Vizcaino, Nicolás M., Dai, Joanne, Barry, Ashley P., Chan, Cliburn, Luftig, Micah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559315/
https://www.ncbi.nlm.nih.gov/pubmed/37561629
http://dx.doi.org/10.1016/j.celrep.2023.112958