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BMP-7 modified exosomes derived from synovial mesenchymal stem cells attenuate osteoarthritis by M2 polarization of macrophages

BACKGROUND: Although the exosomes derived from mesenchymal stem cells (MSCs) display a therapeutic effect on inflammatory diseases, its application on OA has great limitations due to lack of specificity and targeting. The current study aimed to elucidate the potential therapeutic role of bone morpho...

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Detalles Bibliográficos
Autores principales: Sun, Weixue, Qu, Shaozheng, Ji, Mingxia, Sun, Yanli, Hu, Baiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559348/
https://www.ncbi.nlm.nih.gov/pubmed/37809369
http://dx.doi.org/10.1016/j.heliyon.2023.e19934