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Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma

BACKGROUND: Epstein-Barr virus (EBV) is the first discovered human tumor virus that is associated with a variety of malignancies of both lymphoid and epithelial origin including nasopharyngeal carcinoma (NPC). The EBV-encoded latent membrane protein 1 (LMP1) has been well-defined as a potent oncogen...

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Detalles Bibliográficos
Autores principales: Liao, Chaoliang, Li, Min, Chen, Xue, Tang, Chenpeng, Quan, Jing, Bode, Ann M., Cao, Ya, Luo, Xiangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559433/
https://www.ncbi.nlm.nih.gov/pubmed/37803433
http://dx.doi.org/10.1186/s13046-023-02835-6