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Unveiling the biology of defective viral genomes in vitro and in vivo: implications for gene expression and pathogenesis of coronavirus

BACKGROUND: Defective viral genome (DVG) is a truncated version of the full-length virus genome identified in most RNA viruses during infection. The synthesis of DVGs in coronavirus has been suggested; however, the fundamental characteristics of coronavirus DVGs in gene expression and pathogenesis h...

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Detalles Bibliográficos
Autores principales: Lin, Ching-Hung, Chen, BoJia, Chao, Day-Yu, Hsieh, Feng-Cheng, Yang, Chun-Chun, Hsu, Hsuan-Wei, Tam, Hon-Man-Herman, Wu, Hung-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559480/
https://www.ncbi.nlm.nih.gov/pubmed/37803357
http://dx.doi.org/10.1186/s12985-023-02189-7