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Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity

BACKGROUND: Breast cancer is a complex and heterogeneous disease with distinct subtypes and molecular profiles corresponding to different clinical outcomes. Mouse models of breast cancer are widely used, but their relevance in capturing the heterogeneity of human disease is unclear. Previous studies...

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Detalles Bibliográficos
Autores principales: Broeker, Carson D., Ortiz, Mylena M. O., Murillo, Michael S., Andrechek, Eran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559619/
https://www.ncbi.nlm.nih.gov/pubmed/37805590
http://dx.doi.org/10.1186/s13058-023-01723-3