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Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study
OBJECTIVE: The mechanisms of chondrocytes ferroptosis in osteoarthritis (OA) have not yet been fully elucidated. This study aimed to identify key ferroptosis related genes (FRGs) involved in chondrocytes ferroptosis. METHODS: LASSO, SVM-RFE, and receiver operating characteristic curve (ROC) were per...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559678/ https://www.ncbi.nlm.nih.gov/pubmed/37810027 http://dx.doi.org/10.1016/j.heliyon.2023.e19975 |