Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study

OBJECTIVE: The mechanisms of chondrocytes ferroptosis in osteoarthritis (OA) have not yet been fully elucidated. This study aimed to identify key ferroptosis related genes (FRGs) involved in chondrocytes ferroptosis. METHODS: LASSO, SVM-RFE, and receiver operating characteristic curve (ROC) were per...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Peng, Guoxuan, Chen, Kunhao, Xiong, Zhilin, Zhuang, Yong, Liu, Miao, Ning, Xu, Yang, Hua, Deng, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559678/
https://www.ncbi.nlm.nih.gov/pubmed/37810027
http://dx.doi.org/10.1016/j.heliyon.2023.e19975

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