Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR-amplified recurrent glioblastoma patients

BACKGROUND: Glioblastoma (GBM) is a highly aggressive and invasive brain tumor associated with high patient mortality. A large fraction of GBM tumors have been identified as epidermal growth factor receptor (EGFR) amplified and ~50% also are EGFRvIII mutant positive. In a previously reported multice...

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Detalles Bibliográficos
Autores principales: Yekula, Anudeep, Hsia, Tiffaney, Kitchen, Robert R, Chakrabortty, Sudipto K, Yu, Wei, Batool, Syeda M, Lewis, Brian, Szeglowski, Antoni J, Weissleder, Ralph, Lee, Hakho, Chi, Andrew S, Batchelor, Tracy, Carter, Bob S, Breakefield, Xandra O, Skog, Johan, Balaj, Leonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559837/
https://www.ncbi.nlm.nih.gov/pubmed/37811539
http://dx.doi.org/10.1093/noajnl/vdad104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559837/
https://www.ncbi.nlm.nih.gov/pubmed/37811539
http://dx.doi.org/10.1093/noajnl/vdad104

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