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Fasudil and SR1001 synergistically protect against sepsis-associated pancreatic injury by inhibiting RhoA/ROCK pathway and Th17/IL-17 response

Sepsis is defined as a dysregulated host response to infection that can result in organ dysfunction and high mortality, which needs more effective treatment urgently. Pancreas is one of the most vulnerable organs in sepsis, resulting in sepsis-associated pancreatic injury, which is a fatal complicat...

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Detalles Bibliográficos
Autores principales: Liu, Pingping, Xiao, Zhenghui, Lu, Xiulan, Zhang, Xinping, Huang, Jiaotian, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559842/
https://www.ncbi.nlm.nih.gov/pubmed/37809525
http://dx.doi.org/10.1016/j.heliyon.2023.e20118