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Detecting fa leptin receptor mutation in Zucker rats with tetra-primer amplification-refractory mutation system (ARMS)-PCR
Due to the genetic mutation (fa) in the gene encoding for leptin receptor, homozygous Zucker rats (fa(−/−)) develop excessive adiposity and become an experimental animal model in obesity and metabolic-related diseases research. Based on tetra-primer amplification refractory mutation system-polymeras...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559934/ https://www.ncbi.nlm.nih.gov/pubmed/37809507 http://dx.doi.org/10.1016/j.heliyon.2023.e20159 |