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Detecting fa leptin receptor mutation in Zucker rats with tetra-primer amplification-refractory mutation system (ARMS)-PCR

Due to the genetic mutation (fa) in the gene encoding for leptin receptor, homozygous Zucker rats (fa(−/−)) develop excessive adiposity and become an experimental animal model in obesity and metabolic-related diseases research. Based on tetra-primer amplification refractory mutation system-polymeras...

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Detalles Bibliográficos
Autores principales: Xu, Xinyun, Hu, Xinge, Ma, Guodong, Wang, Tiannan, Wu, Jayne, Zhu, Xiaojuan, Chen, Guoxun, Zhao, Ling, Chen, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559934/
https://www.ncbi.nlm.nih.gov/pubmed/37809507
http://dx.doi.org/10.1016/j.heliyon.2023.e20159