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Single-cell data analysis of malignant epithelial cell heterogeneity in lung adenocarcinoma for patient classification and prognosis prediction

Lung cancer is one of the leading causes of cancer-related death. Most advanced lung adenocarcinoma (LUAD) patients have poor survival because of drug resistance and relapse. Neglecting intratumoral heterogeneity might be one of the reasons for treatment insensitivity, while single-cell RNA sequenci...

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Detalles Bibliográficos
Autores principales: Ran, Xu, Tong, Lu, Chenghao, Wang, Qi, Li, Bo, Peng, Jiaying, Zhao, Jun, Wang, Linyou, Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559937/
https://www.ncbi.nlm.nih.gov/pubmed/37809682
http://dx.doi.org/10.1016/j.heliyon.2023.e20164