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Fibronectin promotes tumor progression through integrin αvβ3/PI3K/AKT/SOX2 signaling in non-small cell lung cancer

The tumor microenvironment, especially the extracellular matrix (ECM), is strongly associated with tumor cell proliferation and metastasis. Numerous studies have provided evidence suggesting that fibronectin (FN) in ECM supports cancer cell escape and contributes to cell migration, resulting in dist...

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Detalles Bibliográficos
Autores principales: Wu, Jin-Long, Xu, Cheng-Feng, Yang, Xu-Hui, Wang, Ming-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10559956/
https://www.ncbi.nlm.nih.gov/pubmed/37809806
http://dx.doi.org/10.1016/j.heliyon.2023.e20185