Design, synthesis, anticancer activity and docking studies of novel quinazoline-based thiazole derivatives as EGFR kinase inhibitors

The in vitro anticancer efficacy of a new series of quinazoline-based thiazole derivatives was explored. Three cancer cell lines, MCF-7, HepG2, and A548, as well as the normal Vero cell lines, were tested employing the synthesized quinazoline-based thiazole compounds (4a-j). All of these compounds s...

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Detalles Bibliográficos
Autores principales: Raghu, M.S., Swarup, H.A., Shamala, T., Prathibha, B.S., Kumar, K. Yogesh, Alharethy, Fahd, Prashanth, M.K., Jeon, Byong-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560058/
https://www.ncbi.nlm.nih.gov/pubmed/37809937
http://dx.doi.org/10.1016/j.heliyon.2023.e20300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560058/
https://www.ncbi.nlm.nih.gov/pubmed/37809937
http://dx.doi.org/10.1016/j.heliyon.2023.e20300

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