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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity

BACKGROUND: Hyperactivation of protein tyrosine phosphatase (PTP1B) has been associated with several metabolic malfunctions ranging from insulin resistance, metaflammation, lipotoxicity, and hyperglycaemia. Liver metabolism failure has been proposed as a core element in underlying endocrine disorder...

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Detalles Bibliográficos
Autores principales: Bourebaba, Lynda, Serwotka-Suszczak, Anna, Bourebaba, Nabila, Zyzak, Magdalena, Marycz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560121/
https://www.ncbi.nlm.nih.gov/pubmed/37808009
http://dx.doi.org/10.1155/2023/3803056