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SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?

ABSTRACT: Degenerative ascending aortic aneurysm (AscAA) is a silent and potentially fatal disease characterized by excessive vascular inflammation and fibrosis. We aimed to characterize the cellular and molecular signature for the fibrotic type of endothelial mesenchymal transition (EndMT) that has...

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Detalles Bibliográficos
Autores principales: Freiholtz, David, Bergman, Otto, Pradhananga, Sailendra, Lång, Karin, Poujade, Flore-Anne, Granath, Carl, Olsson, Christian, Franco-Cereceda, Anders, Sahlén, Pelin, Eriksson, Per, Björck, Hanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560177/
https://www.ncbi.nlm.nih.gov/pubmed/37698712
http://dx.doi.org/10.1007/s00109-023-02370-z