Ecological network analysis reveals cancer-dependent chaperone-client interaction structure and robustness

Cancer cells alter the expression levels of metabolic enzymes to fuel proliferation. The mitochondrion is a central hub of metabolic reprogramming, where chaperones service hundreds of clients, forming chaperone-client interaction networks. How network structure affects its robustness to chaperone t...

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Detalles Bibliográficos
Autores principales: Galai, Geut, He, Xie, Rotblat, Barak, Pilosof, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560210/
https://www.ncbi.nlm.nih.gov/pubmed/37805501
http://dx.doi.org/10.1038/s41467-023-41906-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560210/
https://www.ncbi.nlm.nih.gov/pubmed/37805501
http://dx.doi.org/10.1038/s41467-023-41906-2

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