The impact of non-synonymous mutations on miRNA binding sites within the SARS-CoV-2 NSP3 and NSP4 genes

Non-synonymous mutations in the SARS-CoV-2 spike region affect cell entry, tropism, and immune evasion, while frequent synonymous mutations may modify viral fitness. Host microRNAs, a type of non-coding RNA, play a crucial role in the viral life cycle, influencing viral replication and the host immu...

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Detalles Bibliográficos
Autores principales: Rad, S. M. Ali Hosseini, Wannigama, Dhammika Leshan, Hirankarn, Nattiya, McLellan, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560223/
https://www.ncbi.nlm.nih.gov/pubmed/37805621
http://dx.doi.org/10.1038/s41598-023-44219-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560223/
https://www.ncbi.nlm.nih.gov/pubmed/37805621
http://dx.doi.org/10.1038/s41598-023-44219-y

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