A protein kinase C α and β inhibitor blunts hyperphagia to halt renal function decline and reduces adiposity in a rat model of obesity-driven type 2 diabetes

Type 2 diabetes (T2D) and its complications can have debilitating, sometimes fatal consequences for afflicted individuals. The disease can be difficult to control, and therapeutic strategies to prevent T2D-induced tissue and organ damage are needed. Here we describe the results of administering a po...

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Detalles Bibliográficos
Autores principales: Wang, Ju, Casimiro-Garcia, Agustin, Johnson, Bryce G., Duffen, Jennifer, Cain, Michael, Savary, Leigh, Wang, Stephen, Nambiar, Prashant, Lech, Matthew, Zhao, Shanrong, Xi, Li, Zhan, Yutian, Olson, Jennifer, Stejskal, James A., Lin, Hank, Zhang, Baohong, Martinez, Robert V., Masek-Hammerman, Katherine, Schlerman, Franklin J., Dower, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560236/
https://www.ncbi.nlm.nih.gov/pubmed/37805649
http://dx.doi.org/10.1038/s41598-023-43759-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560236/
https://www.ncbi.nlm.nih.gov/pubmed/37805649
http://dx.doi.org/10.1038/s41598-023-43759-7

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