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Chemoproteomic capture of RNA binding activity in living cells

Proteomic methods for RNA interactome capture (RIC) rely principally on crosslinking native or labeled cellular RNA to enrich and investigate RNA-binding protein (RBP) composition and function in cells. The ability to measure RBP activity at individual binding sites by RIC, however, has been more ch...

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Detalles Bibliográficos
Autores principales: Heindel, Andrew J., Brulet, Jeffrey W., Wang, Xiantao, Founds, Michael W., Libby, Adam H., Bai, Dina L., Lemke, Michael C., Leace, David M., Harris, Thurl E., Hafner, Markus, Hsu, Ku-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560261/
https://www.ncbi.nlm.nih.gov/pubmed/37805600
http://dx.doi.org/10.1038/s41467-023-41844-z