Advanced glycation end product (AGE) targeting antibody SIWA318H is efficacious in preclinical models for pancreatic cancer

SIWA318H is a novel monoclonal antibody that selectively targets an advanced glycation end product biomarker found in damaged/dysfunctional cells exhibiting (a) aerobic glycolysis, and (b) oxidative stress. Cells with this biomarker are dysfunctional and are associated with stresses and/or damages r...

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Detalles Bibliográficos
Autores principales: Rossi, Gabriela R., Jensen, Ashley, Ng, Serina, Yin, Zhirong, Li, Aimin, Misra, Anjan, Von Hoff, Daniel D., Gruber, Lewis, Gruber, Misty, Han, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560265/
https://www.ncbi.nlm.nih.gov/pubmed/37805542
http://dx.doi.org/10.1038/s41598-023-44211-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560265/
https://www.ncbi.nlm.nih.gov/pubmed/37805542
http://dx.doi.org/10.1038/s41598-023-44211-6

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