Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury

The current study explores the potential function and the underlying mechanisms of endothelial cell-derived R-spondin 3 (RSPO3) neuroprotection against ischemia/reperfusion-induced neuronal cell injury. In both neuronal cells (Neuro-2a) and primary murine cortical neurons, pretreatment with RSPO3 am...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ting-tao, Shi, Xin, Hu, Hong-wei, Chen, Ju-ping, Jiang, Qin, Zhen, Yun-Fang, Cao, Cong, Liu, Xue-wu, Liu, Jian-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560285/
https://www.ncbi.nlm.nih.gov/pubmed/37805583
http://dx.doi.org/10.1038/s41419-023-06176-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560285/
https://www.ncbi.nlm.nih.gov/pubmed/37805583
http://dx.doi.org/10.1038/s41419-023-06176-2

Ejemplares similares