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Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans

BACKGROUND: Transcription factors (TFs) exhibit heterogeneous DNA-binding specificities in individual cells and whole organisms under natural conditions, and de novo motif discovery usually provides multiple motifs, even from a single chromatin immunoprecipitation-sequencing (ChIP-seq) sample. Despi...

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Detalles Bibliográficos
Autores principales:	Tahara, Saeko, Tsuchiya, Takaho, Matsumoto, Hirotaka, Ozaki, Haruka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560430/ https://www.ncbi.nlm.nih.gov/pubmed/37805453 http://dx.doi.org/10.1186/s12864-023-09692-9

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