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Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress–mitophagy

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is closely associated with steroid hormones and their receptors affected by lipid metabolism. Recently, there has been growing interest in the carcinogenic role of NR3C1, the sole gene responsible for encoding glucocorticoid receptor. However, the...

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Detalles Bibliográficos
Autores principales: Yan, Minbo, Wang, Jinhua, Wang, Haojie, Zhou, Jun, Qi, Hao, Naji, Yaser, Zhao, Liangyu, Tang, Yuxin, Dai, Yingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560440/
https://www.ncbi.nlm.nih.gov/pubmed/37807060
http://dx.doi.org/10.1186/s12967-023-04560-2