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Gentiopicroside ameliorates CCl(4)-induced liver injury in mice by regulating the PPAR-γ/Nrf2 and NF-κB/IκB signaling pathways

OBJECTIVE: This study explored the mechanisms by which gentiopicroside protects against carbon tetrachloride (CCl(4))-induced liver injury. METHODS: Male mice were randomly assigned to the control; CCl(4); bifendate 100 mg/kg; or gentiopicroside 25, 50, or 100 mg/kg groups. Both vehicle and drugs we...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Pan, Shiguang, Yi, Shiming, Sun, Jin, Wang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560445/
https://www.ncbi.nlm.nih.gov/pubmed/37802492
http://dx.doi.org/10.1177/03000605231204501