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Gentiopicroside ameliorates CCl(4)-induced liver injury in mice by regulating the PPAR-γ/Nrf2 and NF-κB/IκB signaling pathways
OBJECTIVE: This study explored the mechanisms by which gentiopicroside protects against carbon tetrachloride (CCl(4))-induced liver injury. METHODS: Male mice were randomly assigned to the control; CCl(4); bifendate 100 mg/kg; or gentiopicroside 25, 50, or 100 mg/kg groups. Both vehicle and drugs we...
Autores principales: | Zhang, Yun, Pan, Shiguang, Yi, Shiming, Sun, Jin, Wang, Haitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560445/ https://www.ncbi.nlm.nih.gov/pubmed/37802492 http://dx.doi.org/10.1177/03000605231204501 |
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