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N-glycoproteomics of brain synapses and synaptic vesicles

At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the major SV glycoproteins synaptophysin and SV2A to SVs. Despite this key role for N-glycosylation, the molecular compositi...

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Detalles Bibliográficos
Autores principales: Bradberry, Mazdak M., Peters-Clarke, Trenton M., Shishkova, Evgenia, Chapman, Edwin R., Coon, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560701/
https://www.ncbi.nlm.nih.gov/pubmed/37036808
http://dx.doi.org/10.1016/j.celrep.2023.112368