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Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

Giardia duodenalis is the causative agent of the neglected diarrhoeal disease giardiasis. While often self-limiting, giardiasis is ubiquitous and impacts hundreds of millions of people annually. It is also a common gastro-intestinal disease of domestic pets, wildlife, and livestock animals. However,...

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Detalles Bibliográficos
Autores principales: Hart, Christopher JS., Riches, Andrew G., Tiash, Snigdha, Abraham, Rebecca, Fayd’Herbe, Keely, Joch, Ellis, Zulfiqar, Bilal, Sykes, Melissa L., Avery, Vicky M., Šlapeta, Jan, Abraham, Sam, Ryan, John H., Skinner-Adams, Tina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560980/
https://www.ncbi.nlm.nih.gov/pubmed/37776606
http://dx.doi.org/10.1016/j.ijpddr.2023.09.002