Selective protein aggregation confines and inhibits endotoxins in wounds: Linking host defense to amyloid formation

Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...

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Detalles Bibliográficos
Autores principales: Petrlova, Jitka, Hartman, Erik, Petruk, Ganna, Lim, Jeremy Chun Hwee, Adav, Sunil Shankar, Kjellström, Sven, Puthia, Manoj, Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561040/
https://www.ncbi.nlm.nih.gov/pubmed/37817942
http://dx.doi.org/10.1016/j.isci.2023.107951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561040/
https://www.ncbi.nlm.nih.gov/pubmed/37817942
http://dx.doi.org/10.1016/j.isci.2023.107951

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