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Selective protein aggregation confines and inhibits endotoxins in wounds: Linking host defense to amyloid formation
Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal m...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561040/ https://www.ncbi.nlm.nih.gov/pubmed/37817942 http://dx.doi.org/10.1016/j.isci.2023.107951 |