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Rutin alleviates ventilator-induced lung injury by inhibiting NLRP3 inflammasome activation

Whether rutin relieves ventilator-induced lung injury (VILI) remains unclear. Here, we used network pharmacology, bioinformatics, and molecular docking to predict the therapeutic targets and potential mechanisms of rutin in the treatment of VILI. Subsequently, a mouse model of VILI was established t...

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Detalles Bibliográficos
Autores principales: Chen, Shengsong, Bai, Yu, Xia, Jingen, Zhang, Yi, Zhan, Qingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561045/
https://www.ncbi.nlm.nih.gov/pubmed/37817937
http://dx.doi.org/10.1016/j.isci.2023.107866