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24-Norursodeoxycholic acid ameliorates experimental alcohol-related liver disease and activates hepatic PPARγ

BACKGROUND & AIMS: Alcohol-related liver disease (ALD) is a global healthcare challenge with limited treatment options. 24-Norursodeoxycholic acid (NorUDCA) is a synthetic bile acid with anti-inflammatory properties in experimental and human cholestatic liver diseases. In the present study, we e...

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Detalles Bibliográficos
Autores principales: Grander, Christoph, Meyer, Moritz, Steinacher, Daniel, Claudel, Thierry, Hausmann, Bela, Pjevac, Petra, Grabherr, Felix, Oberhuber, Georg, Grander, Manuel, Brigo, Natascha, Jukic, Almina, Schwärzler, Julian, Weiss, Günter, Adolph, Timon E., Trauner, Michael, Tilg, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561126/
https://www.ncbi.nlm.nih.gov/pubmed/37818230
http://dx.doi.org/10.1016/j.jhepr.2023.100872