Myddosome clustering in IL‐1 receptor signaling regulates the formation of an NF‐kB activating signalosome

IL‐1 receptor (IL‐1R) signaling can activate thresholded invariant outputs and proportional outputs that scale with the amount of stimulation. Both responses require the Myddosome, a multiprotein complex. The Myddosome is required for polyubiquitin chain formation and NF‐kB signaling. However, how t...

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Detalles Bibliográficos
Autores principales: Cao, Fakun, Deliz‐Aguirre, Rafael, Gerpott, Fenja HU, Ziska, Elke, Taylor, Marcus J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561168/
https://www.ncbi.nlm.nih.gov/pubmed/37602973
http://dx.doi.org/10.15252/embr.202357233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561168/
https://www.ncbi.nlm.nih.gov/pubmed/37602973
http://dx.doi.org/10.15252/embr.202357233

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