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Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease

Intestinal epithelial cells are covered by the brush border, which consists of densely packed microvilli. The Intermicrovillar Adhesion Complex (IMAC) links the microvilli and is required for proper brush border organization. Whether microvillus crosslinking is involved in the intestinal barrier fun...

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Detalles Bibliográficos
Autores principales: Mödl, Bernadette, Awad, Monira, Zwolanek, Daniela, Scharf, Irene, Schwertner, Katharina, Milovanovic, Danijela, Moser, Doris, Schmidt, Katy, Pjevac, Petra, Hausmann, Bela, Krauß, Dana, Mohr, Thomas, Svinka, Jasmin, Kenner, Lukas, Casanova, Emilio, Timelthaler, Gerald, Sibilia, Maria, Krieger, Sigurd, Eferl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561180/
https://www.ncbi.nlm.nih.gov/pubmed/37691494
http://dx.doi.org/10.15252/embr.202357084