Determination of spinal tracer dispersion after intrathecal injection in a deformable CNS model

Background: Traditionally, there is a widely held belief that drug dispersion after intrathecal (IT) delivery is confined locally near the injection site. We posit that high-volume infusions can overcome this perceived limitation of IT administration. Methods: To test our hypothesis, subject-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayansiji, Ayankola O., Gehrke, Daniel S., Baralle, Bastien, Nozain, Ariel, Singh, Meenesh R., Linninger, Andreas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561273/
https://www.ncbi.nlm.nih.gov/pubmed/37817986
http://dx.doi.org/10.3389/fphys.2023.1244016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561273/
https://www.ncbi.nlm.nih.gov/pubmed/37817986
http://dx.doi.org/10.3389/fphys.2023.1244016

Ejemplares similares