Age-dependent changes on fractalkine forms and their contribution to neurodegenerative diseases

The chemokine fractalkine (FKN, CX(3)CL1), a member of the CX(3)C subfamily, contributes to neuron–glia interaction and the regulation of microglial cell activation. Fractalkine is expressed by neurons as a membrane-bound protein (mCX(3)CL1) that can be cleaved by extracellular proteases generating...

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Detalles Bibliográficos
Autores principales: Eugenín, Jaime, Eugenín-von Bernhardi, Laura, von Bernhardi, Rommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561274/
https://www.ncbi.nlm.nih.gov/pubmed/37818457
http://dx.doi.org/10.3389/fnmol.2023.1249320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561274/
https://www.ncbi.nlm.nih.gov/pubmed/37818457
http://dx.doi.org/10.3389/fnmol.2023.1249320

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