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Age-dependent changes on fractalkine forms and their contribution to neurodegenerative diseases
The chemokine fractalkine (FKN, CX(3)CL1), a member of the CX(3)C subfamily, contributes to neuron–glia interaction and the regulation of microglial cell activation. Fractalkine is expressed by neurons as a membrane-bound protein (mCX(3)CL1) that can be cleaved by extracellular proteases generating...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561274/ https://www.ncbi.nlm.nih.gov/pubmed/37818457 http://dx.doi.org/10.3389/fnmol.2023.1249320 |