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Chemical Protein Unfolding – A Simple Cooperative Model

[Image: see text] Chemical unfolding with guanidineHCl or urea is a common method to study the conformational stability of proteins. The analysis of unfolding isotherms is usually performed with an empirical linear extrapolation method (LEM). A large positive free energy is assigned to the native pr...

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Detalles Bibliográficos
Autores principales: Seelig, Joachim, Seelig, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561279/
https://www.ncbi.nlm.nih.gov/pubmed/37735883
http://dx.doi.org/10.1021/acs.jpcb.3c03558