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Chemical Protein Unfolding – A Simple Cooperative Model
[Image: see text] Chemical unfolding with guanidineHCl or urea is a common method to study the conformational stability of proteins. The analysis of unfolding isotherms is usually performed with an empirical linear extrapolation method (LEM). A large positive free energy is assigned to the native pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561279/ https://www.ncbi.nlm.nih.gov/pubmed/37735883 http://dx.doi.org/10.1021/acs.jpcb.3c03558 |