Human BBB-on-a-chip reveals barrier disruption, endothelial inflammation, and T cell migration under neuroinflammatory conditions

The blood-brain barrier (BBB) is a highly selective barrier that ensures a homeostatic environment for the central nervous system (CNS). BBB dysfunction, inflammation, and immune cell infiltration are hallmarks of many CNS disorders, including multiple sclerosis and stroke. Physiologically relevant...

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Detalles Bibliográficos
Autores principales: Nair, Arya Lekshmi, Groenendijk, Linda, Overdevest, Roos, Fowke, Tania M., Annida, Rumaisha, Mocellin, Orsola, de Vries, Helga E., Wevers, Nienke R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561300/
https://www.ncbi.nlm.nih.gov/pubmed/37818458
http://dx.doi.org/10.3389/fnmol.2023.1250123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561300/
https://www.ncbi.nlm.nih.gov/pubmed/37818458
http://dx.doi.org/10.3389/fnmol.2023.1250123

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