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CHK1‐CDC25A‐CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos

After fertilization, remodeling of the oocyte and sperm genomes is essential to convert these highly differentiated and transcriptionally quiescent cells into early cleavage‐stage blastomeres that are transcriptionally active and totipotent. This developmental transition is accompanied by cell cycle...

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Detalles Bibliográficos
Autores principales: Knoblochova, Lucie, Duricek, Tomas, Vaskovicova, Michaela, Zorzompokou, Chrysoula, Rayova, Diana, Ferencova, Ivana, Baran, Vladimir, Schultz, Richard M, Hoffmann, Eva R, Drutovic, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561370/
https://www.ncbi.nlm.nih.gov/pubmed/37694680
http://dx.doi.org/10.15252/embr.202256530