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CHK1‐CDC25A‐CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos
After fertilization, remodeling of the oocyte and sperm genomes is essential to convert these highly differentiated and transcriptionally quiescent cells into early cleavage‐stage blastomeres that are transcriptionally active and totipotent. This developmental transition is accompanied by cell cycle...
Autores principales: | Knoblochova, Lucie, Duricek, Tomas, Vaskovicova, Michaela, Zorzompokou, Chrysoula, Rayova, Diana, Ferencova, Ivana, Baran, Vladimir, Schultz, Richard M, Hoffmann, Eva R, Drutovic, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561370/ https://www.ncbi.nlm.nih.gov/pubmed/37694680 http://dx.doi.org/10.15252/embr.202256530 |
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