Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalk

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is characterised by limited responses to chemoimmunotherapy attributed to highly desmoplastic tumor microenvironment. Disrupting the tumor-stromal cell crosstalk is considered as an improved PDAC treatment strategy, whereas little progress has been...

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Detalles Bibliográficos
Autores principales: Qin, Hongquan, Chen, Jiali, Bouchekioua-Bouzaghou, Katia, Meng, Ya-Ming, Griera, Jordi Bach, Jiang, Xue, Kong, Xiangzhan, Wang, Minghui, Xu, Qiuping, Wong, Ping-Pui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561406/
https://www.ncbi.nlm.nih.gov/pubmed/37814317
http://dx.doi.org/10.1186/s12967-023-04519-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561406/
https://www.ncbi.nlm.nih.gov/pubmed/37814317
http://dx.doi.org/10.1186/s12967-023-04519-3

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