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Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalk

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is characterised by limited responses to chemoimmunotherapy attributed to highly desmoplastic tumor microenvironment. Disrupting the tumor-stromal cell crosstalk is considered as an improved PDAC treatment strategy, whereas little progress has been...

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Detalles Bibliográficos
Autores principales:	Qin, Hongquan, Chen, Jiali, Bouchekioua-Bouzaghou, Katia, Meng, Ya-Ming, Griera, Jordi Bach, Jiang, Xue, Kong, Xiangzhan, Wang, Minghui, Xu, Qiuping, Wong, Ping-Pui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561406/ https://www.ncbi.nlm.nih.gov/pubmed/37814317 http://dx.doi.org/10.1186/s12967-023-04519-3

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