scIBD: a self-supervised iterative-optimizing model for boosting the detection of heterotypic doublets in single-cell chromatin accessibility data

Application of the widely used droplet-based microfluidic technologies in single-cell sequencing often yields doublets, introducing bias to downstream analyses. Especially, doublet-detection methods for single-cell chromatin accessibility sequencing (scCAS) data have multiple assay-specific challeng...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenhao, Jiang, Rui, Chen, Shengquan, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561408/
https://www.ncbi.nlm.nih.gov/pubmed/37814314
http://dx.doi.org/10.1186/s13059-023-03072-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561408/
https://www.ncbi.nlm.nih.gov/pubmed/37814314
http://dx.doi.org/10.1186/s13059-023-03072-y

Ejemplares similares