Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

BACKGROUND: Abdominal obesity is appreciated as a major player in insulin resistance and metabolically dysfunctional adipose tissue. Inappropriate extracellular matrix (ECM) remodelling and functional alterations in human adipose stromal/stem cells (hASCs) have been linked with visceral white adipos...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xueya, Li, Weihong, He, Xu, Lu, Xin, Zhang, Yu, Li, Yaqiong, Bi, Guoyun, Ma, Xuqing, Huang, Xiaowu, Bai, Rixing, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561428/
https://www.ncbi.nlm.nih.gov/pubmed/37807066
http://dx.doi.org/10.1186/s13287-023-03525-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561428/
https://www.ncbi.nlm.nih.gov/pubmed/37807066
http://dx.doi.org/10.1186/s13287-023-03525-y

Ejemplares similares