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Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

BACKGROUND: Abdominal obesity is appreciated as a major player in insulin resistance and metabolically dysfunctional adipose tissue. Inappropriate extracellular matrix (ECM) remodelling and functional alterations in human adipose stromal/stem cells (hASCs) have been linked with visceral white adipos...

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Detalles Bibliográficos
Autores principales:	Han, Xueya, Li, Weihong, He, Xu, Lu, Xin, Zhang, Yu, Li, Yaqiong, Bi, Guoyun, Ma, Xuqing, Huang, Xiaowu, Bai, Rixing, Zhang, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561428/ https://www.ncbi.nlm.nih.gov/pubmed/37807066 http://dx.doi.org/10.1186/s13287-023-03525-y

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