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Relative abundance data can misrepresent heritability of the microbiome

BACKGROUND: Host genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important question can be addressed by estimating the heritability (h(2)) of the microbiome—the proportion of variance in the abundance in each taxon that is at...

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Detalles Bibliográficos
Autores principales: Bruijning, Marjolein, Ayroles, Julien F., Henry, Lucas P., Koskella, Britt, Meyer, Kyle M., Metcalf, C. Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561453/
https://www.ncbi.nlm.nih.gov/pubmed/37814275
http://dx.doi.org/10.1186/s40168-023-01669-w