Ubiquitin-specific peptidase 25 exacerbated osteoarthritis progression through facilitating TXNIP ubiquitination and NLRP3 inflammasome activation

Several members of the ubiquitin-specific proteases (USPs) family have been revealed to regulate the progression of osteoarthritis (OA). The current study aimed to investigate the role and the underlying mechanism of USP25 in IL-1β-induced chondrocytes and OA rat model. It was discovered that IL-1β...

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Detalles Bibliográficos
Autores principales: Sui, Jie, Dai, Fei, Shi, Jiusheng, Zhou, Changcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561454/
https://www.ncbi.nlm.nih.gov/pubmed/37814350
http://dx.doi.org/10.1186/s13018-023-04083-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561454/
https://www.ncbi.nlm.nih.gov/pubmed/37814350
http://dx.doi.org/10.1186/s13018-023-04083-y

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