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Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry

INTRODUCTION: Vasculogenic mimicry (VM), the process of tumor cell transdifferentiation to endow endothelial-like characteristics supporting de novo vessel formation, is associated with poor prognosis in several tumor types, including SCLC. In genetically engineered mouse models (GEMMs) of SCLC, NOT...

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Detalles Bibliográficos
Autores principales: Pearsall, Sarah M., Williamson, Stuart C., Humphrey, Sam, Hughes, Ellyn, Morgan, Derrick, Marqués, Fernando J. García, Awanis, Griselda, Carroll, Rebecca, Burks, Laura, Shue, Yan Ting, Bermudez, Abel, Frese, Kristopher K., Galvin, Melanie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Zhou, Cong, Oliver, Trudy G., Humphries, Jonathan D., Humphries, Martin J., Blackhall, Fiona, Cannell, Ian G., Pitteri, Sharon J., Hannon, Gregory J., Sage, Julien, Dive, Caroline, Simpson, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561473/
https://www.ncbi.nlm.nih.gov/pubmed/37455012
http://dx.doi.org/10.1016/j.jtho.2023.07.012