Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy

Cells harness multiple pathways to maintain lysosome integrity, a central homeostatic process. Damaged lysosomes can be repaired or targeted for degradation by lysophagy, a selective autophagy process involving ATG8/LC3. Here, we describe a parallel ATG8/LC3 response to lysosome damage, mechanistica...

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Detalles Bibliográficos
Autores principales: Cross, Jake, Durgan, Joanne, McEwan, David G., Tayler, Matthew, Ryan, Kevin M., Florey, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561555/
https://www.ncbi.nlm.nih.gov/pubmed/37796195
http://dx.doi.org/10.1083/jcb.202303078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561555/
https://www.ncbi.nlm.nih.gov/pubmed/37796195
http://dx.doi.org/10.1083/jcb.202303078

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